Synthesis of Alkylthio Benzene Derivatives Via Simultaneous Diazotization and Nucleophilic Displacement

Alkylthio benzene derivatives were effectively synthesized by simultaneous diazotization of aromatic amines and nucleophilic displacement. The method is fairly general proceeds in moderate yields. Product yields comparable regardless steric hindrance the thiol or functional group present starting material. newly developed procedure allowed for incorporation a tertiary alkylthio group, which cannot be easily introduced otherwise. products characterized 1H NMR 13C NMR.